Antigen presentation: Peptides and proteins scramble for the exit
نویسندگان
چکیده
The fate of peptides that fail to bind to major histocompatibility complex class I molecules in the endoplasmic reticulum (ER)has remained unclear. A recent study has revealed that these peptides exit the ER via the Sec61 channel and compete for this pathway with misfolded proteins.
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عنوان ژورنال:
- Current Biology
دوره 10 شماره
صفحات -
تاریخ انتشار 2000